2024
Tsap MI, Yatsenko AS, Hegermann J, Beckmann B, Tsikas D, Shcherbata HR. Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier. Elife. 2024 Apr 25;13:e98020. doi: 10.7554/eLife.98020. PubMed
Stephan T, Stoldt S, Barbot M, Carney TD, Lange F, Bates M, Bou Dib P, Inamdar K, Shcherbata HR, Meinecke M, Riedel D, Dennerlein S, Rehling P, Jakobs S. Drosophila MIC10b can polymerize into cristae-shaping filaments. Life Sci Alliance. 2024 Jan 22;7(4):e202302177. doi: 10.26508/lsa.202302177. Print 2024 Apr. PubMed
2023
Travis D Carney, Rucha Y Hebalkar, Evgeniia Edeleva, Ibrahim Ömer Çiçek, Halyna R Shcherbata Signaling through the Dystrophin Glycoprotein Complex affects the stress-dependent transcriptome in Drosophila. Dis Model Mech. 2023 Jan 3;dmm.049862. doi: 10.1242/dmm.049862 PubMed
2022
Ana-Maria Zamfirescu, Andriy S Yatsenko, Halyna R Shcherbata Notch signaling sculpts the stem cell niche. Front Cell Dev Biol. 2022 Dec 20;10:1027222. doi: 10.3389/fcell.2022.1027222. PubMed
Stoika R, Gudimchuk N, Shcherbata HR, Zaraisky A, Shcheglovitov O, Kozorovitskiy Y, Korolchuk V. The voices of Ukrainian and Russian scientists. Cell. 2022 Apr 14;185(8):1283-1286. doi: 10.1016/j.cell.2022.03.036. Epub 2022 Apr 6.PMID: 35390273 PubMed
Shcherbata HR. The Russian invasion of Ukraine: a humanitarian tragedy and a tragedy for science. EMBO Rep. 2022 May 4;23(5):e55164. doi: 10.15252/embr.202255164. PubMed
Karki P, Carney TD, Maracci C, Yatsenko AS, Shcherbata HR, Rodnina MV. Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor. Nucleic Acids Res. 2022 Jun 24;50(11):6001-6019. doi: 10.1093/nar/gkab1189. PubMed
2021
Melentev PA, Ryabova EV, Surina NV, Zhmujdina DR, Komissarov AE, Ivanova EA, Boltneva NP, Makhaeva GF, Sliusarenko MI, Yatsenko AS, Mohylyak II, Matiytsiv NP, Shcherbata HR, Sarantseva SV. Loss of swiss cheese in Neurons Contributes to Neurodegeneration with Mitochondria Abnormalities, Reactive Oxygen Species Acceleration and Accumulation of Lipid Droplets in Drosophila Brain. Int J Mol Sci. 2021 Jul 31;22(15):8275. doi: 10.3390/ijms22158275. PubMed
Yatsenko AS, Shcherbata HR. Distant activation of Notch signaling induces stem cell niche assembly. PLoS Genet. 2021 Mar 29;17(3):e1009489. PubMed
Ryabova EV, Melentev PA, Komissarov AE, Surina NV, Ivanova EA, Matiytsiv N, Shcherbata HR, Sarantseva SV. Morpho-Functional Consequences of Swiss Cheese Knockdown in Glia of Drosophila melanogaster. Cells. 2021 Mar 2;10(3):529. PubMed
Yatsenko AS, Kucherenko MM, Xie Y, Urlaub H, Shcherbata HR. Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. Elife. 2021 Feb 23;10:e63868 PubMed
Petriv N, Neubert L, Vatashchuk M, Timrott K, Suo H, Hochnadel I, Huber R, Petzold C, Hrushchenko A, Yatsenko AS, Shcherbata HR, Wedemeyer H, Lichtinghagen R, Falfushynska H, Lushchak V, Manns MP, Bantel H, Semchyshyn H, Yevsa T. Increase of alpha-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer. Oncoimmunology. 2021 Feb 8;10(1):1874159. PubMed
2020
Yatsenko AS, Kucherenko MM, Xie Y, Aweida D, Urlaub H, Scheibe RJ, Cohen S, Shcherbata HR: Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. BMC Med 2020, 18(1):8. PubMed
2019
Shcherbata HR: miRNA functions in stem cells and their niches: lessons from the Drosophila ovary. Curr Opin Insect Sci 2019, 31:29-36. PubMed
2018
Yatsenko AS, Shcherbata HR: Stereotypical architecture of the stem cell niche is spatiotemporally established by miR-125-dependent coordination of Notch and steroid signaling. Development 2018, 145(3). PubMed
Kucherenko MM, Shcherbata HR: Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival. Nat Commun 2018, 9(1):312. PubMed
Kucherenko MM, Shcherbata HR: miRNA targeting and alternative splicing in the stress response – events hosted by membrane-less compartments. J Cell Sci 2018, 131(4). PubMed
2017
Kreipke RE, Kwon YV, Shcherbata HR, Ruohola-Baker H: Drosophila melanogaster as a Model of Muscle Degeneration Disorders. Curr Top Dev Biol 2017, 121:83-109. PubMed
2016
Kucherenko MM, Ilangovan V, Herzig B, Shcherbata HR, Bringmann H: TfAP-2 is required for night sleep in Drosophila. BMC Neurosci 2016, 17(1):72. PubMed
Cicek IO, Karaca S, Brankatschk M, Eaton S, Urlaub H, Shcherbata HR: Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Genetics 2016, 202(3):1167-1183. PubMed
2015
Konig A, Shcherbata HR: Soma influences GSC progeny differentiation via the cell adhesion-mediated steroid-let-7-Wingless signaling cascade that regulates chromatin dynamics. Biol Open 2015, 4(3):285-300. PubMed
2014
Yatsenko AS, Shcherbata HR: Drosophila miR-9a targets the ECM receptor Dystroglycan to canalize myotendinous junction formation. Dev Cell 2014, 28(3):335-348. PubMed
Yatsenko AS, Marrone AK, Shcherbata HR: miRNA-based buffering of the cobblestone-lissencephaly-associated extracellular matrix receptor dystroglycan via its alternative 3′-UTR. Nat Commun 2014, 5:4906. PubMed
Yatsenko AS, Marrone AK, Kucherenko MM, Shcherbata HR: Measurement of metabolic rate in Drosophila using respirometry. J Vis Exp 2014(88):e51681. PubMed Video
Fagegaltier D, Konig A, Gordon A, Lai EC, Gingeras TR, Hannon GJ, Shcherbata HR: A genome-wide survey of sexually dimorphic expression of Drosophila miRNAs identifies the steroid hormone-induced miRNA let-7 as a regulator of sexual identity. Genetics 2014, 198(2):647-668. PubMed
2013
Kucherenko MM, Shcherbata HR: Steroids as external temporal codes act via microRNAs and cooperate with cytokines in differential neurogenesis. Fly (Austin) 2013, 7(3):173-183. PubMed
Konig A, Shcherbata HR: Visualization of adult stem cells within their niches using the Drosophila germline as a model system. Methods Mol Biol 2013, 1035:25-33. PubMed
Edeleva EV, Shcherbata HR: Stress-induced ECM alteration modulates cellular microRNAs that feedback to readjust the extracellular environment and cell behavior. Front Genet 2013, 4:305. PubMed
2012
Marrone AK, Edeleva EV, Kucherenko MM, Hsiao NH, Shcherbata HR: Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile. BMC Cell Biol 2012, 13:26. PubMed
Kucherenko MM, Barth J, Fiala A, Shcherbata HR: Steroid-induced microRNA let-7 acts as a spatio-temporal code for neuronal cell fate in the developing Drosophila brain. EMBO J 2012, 31(24):4511-4523. PubMed
Karpiuk O, Najafova Z, Kramer F, Hennion M, Galonska C, Konig A, Snaidero N, Vogel T, Shchebet A, Begus-Nahrmann Y et al: The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Mol Cell 2012, 46(5):705-713. PubMed
2011
Marrone AK, Shcherbata HR: Dystrophin Orchestrates the Epigenetic Profile of Muscle Cells Via miRNAs. Front Genet 2011, 2:64. PubMed
Marrone AK, Kucherenko MM, Wiek R, Gopfert MC, Shcherbata HR: Hyperthermic seizures and aberrant cellular homeostasis in Drosophila dystrophic muscles. Sci Rep 2011, 1:47. PubMed
Marrone AK, Kucherenko MM, Rishko VM, Shcherbata HR: New dystrophin/dystroglycan interactors control neuron behavior in Drosophila eye. BMC Neurosci 2011, 12:93. PubMed
Kucherenko MM, Marrone AK, Rishko VM, Magliarelli Hde F, Shcherbata HR: Stress and muscular dystrophy: a genetic screen for dystroglycan and dystrophin interactors in Drosophila identifies cellular stress response components. Dev Biol 2011, 352(2):228-242. PubMed
Konig A, Yatsenko AS, Weiss M, Shcherbata HR: Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation. EMBO J 2011, 30(8):1549-1562. PubMed
2010
Kucherenko MM, Marrone AK, Rishko VM, Yatsenko AS, Klepzig A, Shcherbata HR: Paraffin-embedded and frozen sections of Drosophila adult muscles. J Vis Exp 2010(46). PubMed Video
2009
Yu JY, Reynolds SH, Hatfield SD, Shcherbata HR, Fischer KA, Ward EJ, Long D, Ding Y, Ruohola-Baker H: Dicer-1-dependent Dacapo suppression acts downstream of Insulin receptor in regulating cell division of Drosophila germline stem cells. Development 2009, 136(9):1497-1507. PubMed
Yatsenko AS, Kucherenko MM, Pantoja M, Fischer KA, Madeoy J, Deng WM, Schneider M, Baumgartner S, Akey J, Shcherbata HR et al: The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function. BMC Dev Biol 2009, 9:18. PubMed
Qi J, Yu JY, Shcherbata HR, Mathieu J, Wang AJ, Seal S, Zhou W, Stadler BM, Bourgin D, Wang L et al: microRNAs regulate human embryonic stem cell division. Cell Cycle 2009, 8(22):3729-3741. PubMed
2008
Kucherenko MM, Pantoja M, Yatsenko AS, Shcherbata HR, Fischer KA, Maksymiv DV, Chernyk YI, Ruohola-Baker H: Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex. PLoS One 2008, 3(6):e2418. PubMed
2007
Yatsenko AS, Gray EE, Shcherbata HR, Patterson LB, Sood VD, Kucherenko MM, Baker D, Ruohola-Baker H: A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila. J Biol Chem 2007, 282(20):15159-15169. PubMed
Shcherbata HR, Yatsenko AS, Patterson L, Sood VD, Nudel U, Yaffe D, Baker D, Ruohola-Baker H: Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy. EMBO J 2007, 26(2):481-493. PubMed
Shcherbata HR, Ward EJ, Fischer KA, Yu JY, Reynolds SH, Chen CH, Xu P, Hay BA, Ruohola-Baker H: Stage-specific differences in the requirements for germline stem cell maintenance in the Drosophila ovary. Cell Stem Cell 2007, 1(6):698-709. PubMed
2006
Ward EJ, Shcherbata HR, Reynolds SH, Fischer KA, Hatfield SD, Ruohola-Baker H: Stem cells signal to the niche through the Notch pathway in the Drosophila ovary. Curr Biol 2006, 16(23):2352-2358. PubMed
Shcherbata HR, Hatfield S, Ward EJ, Reynolds S, Fischer KA, Ruohola-Baker H: The MicroRNA pathway plays a regulatory role in stem cell division. Cell Cycle 2006, 5(2):172-175. PubMed
2005
Hatfield SD, Shcherbata HR, Fischer KA, Nakahara K, Carthew RW, Ruohola-Baker H: Stem cell division is regulated by the microRNA pathway. Nature 2005, 435(7044):974-978. PubMed
2004
Shcherbata HR, Althauser C, Findley SD, Ruohola-Baker H: The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell-cycle transitions. Development 2004, 131(13):3169-3181. PubMed
Shcherbata GR, Matiitsiv NP, Chernik Ia I, Maksimiv DV: [Chemically induced Drosophila melanogaster mutants with changes in brain structure]. Genetika 2004, 40(9):1280-1285. PubMed
Halyna Shcherbata 